If your acoustic guitar has a 'standard' output, that you might normally connect to a guitar amp, or into a recording mixer, etc, then it should be compatible. But you don't say what any of the actual devices are.

As far as the vst plugins are concerned, there seem to be three different types of thing. Some plugins may do more that one of these.

On the face of it, you're asking about a plugin that will receive an audio signal (which COULD be from a guitar, but could be from anything else, even voice via a microphone), and convert this to midi (note number, on and off, and velocity/volume). Such devices have been about for a long time, although I'd expect they are more sophisticated now. How well they work will depend on the cost and the quality/control you can exert. I have a Roland CP-40 device I got long ago, this could take guitar input, or anything via a mic, and YES, it works, but it was never practical. Basically, I cannot play anything properly, and the device was picking up ALL the detail of the noises I was making, so I got a MASS of midi data that was all over the place. Maybe if I was MASSIVELY better at playing. I would get more useful midi data. Possibly more modern devices have better software, etc, to allow for more selective conversion, I don't know. I'm still pretty sure the problem was ME!

There are however other types of VST. Some are in effect a guitar synthesiser, they contain sampled guitar sounds, you play your guitar (as in effect a midi controller) and the sound that comes out is really the sound of the sampled instruments. Such a device within a DAW could also, I'd assume - record midi information converted from the audio data. Others are in effect a sort of digital recorder, the sound of you playing your guitar is recorded digitally as saved as part of your project (within your DAW system).

Geoff