Is the file you refer to playing a midi file? If so, it might help if you could attach it so it can be checked, and/or tested with other devices?
Otherwise, the problem you describe could relate to something that is not initially on (active), and is then activated without enough time to become ready. The only think I can suggest just now is to try to determine which device this might be, and maybe turn it on sometime before it is first needed, maybe to play a dummy none (i.e. play a note but very quiet/brief) and leave it active ready for the real note/sound in measure 69.
Geoff
If you have the option to adjust playback speed, you can also try playing it slower to see if it still happens, like 50 or 25 percent speed. That can potentially help narrow down a timing issue if there's just too much stuff happening at once.
If it's easy enough to do, you can also temporarily changes those instruments to something else and see if the issue persists with other instrument samples.
I'm not sure if this is a hardware or software issue. When I open a file and play it, the first time it plays there's a glitch in the cellos and/or basses at measure 69 (the work is in progress and I am up to around measure 130 or so). But if I go back and play just those measures or the entire sequence, it plays fine for the entire session.
I've done a check on my hardware in terms of how well it's able to handle audio and everything looks good. Though I've been managing a studio for nearly 40 years, I'm really stumped as to what causes this. My DAW is connected to one other machine that is dedicated to the Vienna Symphonic Orchestral Cube.
DAW:
Windows 10, i7 CPU, 32 GB RAM, 2 SSD drives
2nd Computer:
Windows 10, i7 CPU, 32 GB RAM, 3 SSD drives
The two computers are connected via ADAT, each machine has a dedicated sound car, the DAW has an RME UFX II and the 2nd computer has a MOTU LP32. I've tried changing the audio buffers from 512 to 1024 but that doesn't resolve it.
These are dedicated computers, used for nothing but music production.
I really don't know if this is an audio glitch or a MIDI glitch. It sounds like a note gets cut off and I hear a little short "pop". As I said, this only happens once, when I playback the file the first time after I turn the computer on and begin work.
I could try reinstalling the samples of those instruments, but if the sample file(s) got corrupted, I'd think they'd not play back correctly every time.
Any thoughts from what might be causing this?
Thanks,
Jerry