Part of making MIDI guitar feel “right” when triggering synths has nothing to do with the guitar and its tracking, but with editing the synth presets so that they’re guitar-friendly instead of being optimized with keyboards in mind.
Separate channels. The guitar will most likely send data from each string over a different channel. So, use synths in multitimbral mode, where each voice has its own channel. Depending on the synth, the fastest way to do this is to optimize a voice for one string on one channel, then copy over to the other channels.
Polyphony. Set each voice for one-note polyphony. Think about it—with any guitar, you can’t play more than one note at a time on a given string. MIDI guitar feels more realistic when it responds in the same way (and may even appear to track better).
Legato mode. If there’s a legato mode, consider using it. Then if you slide up the neck, you won’t retrigger a note at every fret along the way…then again, maybe that’s the effect you want.
If you don’t want to program the sounds yourself East West has released a series of sounds specifically programmed for MIDI guitar.
EastWest MIDI Guitar Series Volume 1 Orchestra | Sweetwater